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Treating fibrotic disease and restoring organ function
About
Kleis develops oral therapies that stop fibrosis at its source, tackling a process that drives many chronic, life‑limiting diseases.
TG2 proteins resist natural breakdown and build up in tissues; a hallmark of conditions like fibrostenosing Crohn’s, cardiac fibrosis, chronic kidney disease and Idiopathic pulmonary fibrosis (IPF).
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The outlook for patients with these diseases is either surgery or organ failure leading to transplant or death. Outcomes affecting hundreds of millions worldwide.
Kleis is working towards a future where fibrosis can be reversed and people can live longer, healthier lives.
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